VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

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Human mastadenovirus B

Family: Adenoviridae

Receptor: CD46

Receptor CD46 information

Summary: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0035 2021.04 10X Genomics Duodenum Normal 1482 Link
Vthunter_0036 2021.04 10X Genomics Esophagus Normal 24581 Link
Vthunter_0037 2021.04 10X Genomics Heart Normal 12958 Link
Vthunter_0038 2021.04 10X Genomics Kidney Normal 4481 Link
Vthunter_0039 2021.04 10X Genomics LargeIntestine Normal 3328 Link
Vthunter_0040 2021.04 10X Genomics Liver Normal 5694 Link
Vthunter_0041 2021.04 10X Genomics Lung Normal 13720 Link
Vthunter_0042 2021.04 10X Genomics Spleen Normal 3207 Link
Vthunter_0043 2021.04 10X Genomics Stomach Normal 12485 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CD46 in human tissues   [NCBI]

Expression: Ubiquitous expression in adrenal (RPKM 99.0), placenta (RPKM 71.8) and 25 other tissues?

Protein expression of CD46 in human tissues   [Proteinatlas]